Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1925890 | 0.82 | LMNA (0.43) | GAAHPGDKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL20664204 | 0.81 | GAA (0.45) | GAAHPGDKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL21524696 | 0.75 | HPGD (0.55) | GAAHPGDKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL3362244 | 0.73 | HPGD (0.57) | GAAHPGDKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL1925235 | 0.72 | NAPRT (0.46) | KMT2ASMN1; SMN2HTTALDH1A1MAPT | |
| SCHEMBL1925496 | 0.70 | ATM (0.46) | GAAKMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL26610860 | 0.69 | TSHR (0.52) | GAAHPGDKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL1926122 | 0.68 | ITGAV (0.40) | KMT2AMEN1CA1CA2CA9 | |
| Hydrochloric Acid SCHEMBL28261327 | 0.68 | TSHR (0.50) | GAAHPGDKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL10078922 | 0.67 | HPGD (0.53) | GAAHPGDKMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2509941-B1 | N-ACYLATED HYDROXYLAMINE DERIVATIVES AND O-ACYLATED HYDROXYLAMINE DERIVATIVES | UNIV JOHNS HOPKINS (US) | 2019-01-23 | — | — | EP | disclosed |