1,3-Propanediol

1,3-Propanediol

SCHEMBL2066434

CCC(O)O.OCCCO

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.47
SMN1; SMN2 Q16637 1/20 0.44
TSHR P16473 6/20 0.42
LMNA P02545 3/20 0.42
HSD17B10 Q99714 1/20 0.42
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1,4-Butanediol SCHEMBL18007026 0.93 SMN1; SMN2 (0.53) ALDH1A1SMN1; SMN2TSHRLMNAHSD17B10
1,4-Butanediol SCHEMBL9614932 0.90 SMN1; SMN2 (0.50) ALDH1A1SMN1; SMN2TSHRLMNAHSD17B10
Ethylene Glycol SCHEMBL23388166 0.85 TSHR (0.47) ALDH1A1SMN1; SMN2TSHRLMNAHSD17B10
Ethylene Glycol SCHEMBL5476239 0.85
1,4-Butanediol SCHEMBL9614930 0.84 SMN1; SMN2 (0.45) ALDH1A1SMN1; SMN2TSHRLMNAHSD17B10
1-Hexanol SCHEMBL8436853 0.82 LMNA (0.72) ALDH1A1SMN1; SMN2TSHRLMNAHSD17B10
Propanol SCHEMBL11239060 0.81
Alcohol SCHEMBL9548516 0.81
SCHEMBL9004510 0.81
SCHEMBL16959 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2002034704-A2 HYDROXY-ALKANOIC ACID ESTER MONOMER COMPOSITIONS AND METHODS OF MAKING SAME METABOLIX, INC. (US) 2002-05-02 WO claimed
US-8148569-B1 Guerbet citrate polyesters SURFATECH CORPORATION (US) 2012-04-03 US disclosed
EP-1216083-B1 RECOVERY PROCESS FOR VOLATILE COMPOUNDS FROM SOLIDS IN AQUEOUS SOLUTION DU PONT (US) 2007-07-25 EP disclosed
US-6231976-B1 BLENDS CONTAINING CYCLOHEXANEDIMETHANOL EASTMAN CHEMICAL COMPANY 2001-05-15 US disclosed
US-5225387-A Hydroformylation UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1993-07-06 US disclosed