Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.76 |
| ▸ | MAPT | P10636 | 7/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.69 |
| ▸ | TP53 | P04637 | 4/20 | 0.69 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.67 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.67 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.67 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.67 |
| ▸ | MAOB | P27338 | 5/20 | 0.65 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.64 |
| ▸ | MEN1 | O00255 | 4/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | FLT3 | P36888 | 4/20 | 0.62 |
| ▸ | NPC1 | O15118 | 4/20 | 0.62 |
| ▸ | RAB9A | P51151 | 4/20 | 0.62 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.62 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20100895 | 0.88 | ABCB1 (0.82) | ADORA3MAPTCYP3A4SMN1; SMN2TP53 | |
| SCHEMBL20868304 | 0.86 | MAPT (0.79) | ADORA3MAPTCYP3A4SMN1; SMN2TP53 | |
| SCHEMBL20664434 | 0.86 | ADORA3 (1.00) | ADORA3MAPTCYP3A4SMN1; SMN2TP53 | |
| SCHEMBL28588026 | 0.84 | CYP3A4 (0.62) | ADORA3MAPTCYP3A4SMN1; SMN2TP53 | |
| SCHEMBL28568538 | 0.82 | CYP3A4 (0.72) | ADORA3MAPTCYP3A4SMN1; SMN2TP53 | |
| Methoxyvone SCHEMBL3409370 | 0.82 | CYP3A4 (1.00) | ADORA3MAPTCYP3A4SMN1; SMN2TP53 | |
| Methoxyvone SCHEMBL29373562 | 0.82 | CYP3A4 (1.00) | ADORA3MAPTCYP3A4SMN1; SMN2TP53 | |
| SCHEMBL13479744 | 0.81 | CSNK2A2 (0.64) | ADORA3MAPTCYP3A4SMN1; SMN2TP53 | |
| SCHEMBL16521507 | 0.81 | MAPT (0.71) | ADORA3MAPTCYP3A4SMN1; SMN2TP53 | |
| SCHEMBL15268315 | 0.80 | MAOB (0.68) | ADORA3MAPTCYP3A4SMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2828248-B1 | FLAVONE DERIVATIVES AND THEIR USE | TWINCORE GMBH (DE) | 2019-01-23 | — | — | EP | disclosed |