Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 13/20 | 0.46 |
| ▸ | MAOA | P21397 | 11/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15716037 | 0.80 | MAOB (0.46) | MAOBMAOAMCL1GRM4MEN1 | |
| SCHEMBL23141200 | 0.76 | AR (0.45) | MAOBMAOAMCL1KDM4EAR | |
| SCHEMBL15716232 | 0.76 | MAOB (0.49) | MAOBMAOAKDM4ECYP1A2CYP3A4 | |
| SCHEMBL20756137 | 0.73 | TRPV4 (0.53) | MAOBMAOAKDM4EMEN1CYP1A2 | |
| SCHEMBL206187 | 0.72 | CYP2A6 (0.44) | MAOBMAOAMCL1GRM4KDM4E | |
| SCHEMBL20755909 | 0.72 | TRPV4 (0.52) | MAOBMAOAAR | |
| SCHEMBL22168373 | 0.72 | TSHR (0.43) | MAOBMAOAAR | |
| SCHEMBL1343188 | 0.72 | MAOB (0.44) | MAOBMAOAMCL1GRM4MEN1 | |
| SCHEMBL31235647 | 0.70 | MEN1 (0.43) | MAOBMAOAGRM4MEN1KMT2A | |
| SCHEMBL3836763 | 0.70 | MEN1 (0.43) | MAOBMAOAGRM4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3431474-A1 | CHEMICAL COMPOUNDS | Antabio SAS (FR) | 2019-01-23 | — | — | EP | disclosed |