Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | NAAA | Q02083 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | ME2 | P23368 | 1/20 | 0.52 |
| ▸ | ME1 | P48163 | 1/20 | 0.52 |
| ▸ | ME3 | Q16798 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | KDM1A | O60341 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7131839 | 0.81 | NPC1 (0.86) | NPC1TDP1FKBP1APOLBNAAA | |
| SCHEMBL1838692 | 0.80 | NPC1 (0.73) | NPC1TDP1FKBP1APOLBNAAA | |
| SCHEMBL16615993 | 0.80 | ENPP2 (0.61) | FKBP1AKMT2AMEN1ALDH1A1EPHX2 | |
| Hydrochloric Acid SCHEMBL16616458 | 0.80 | ENPP2 (0.56) | NPC1TDP1KMT2AMAPTMEN1 | |
| Hydrochloric Acid SCHEMBL3086821 | 0.79 | NPC1 (0.71) | NPC1TDP1FKBP1APOLBNAAA | |
| SCHEMBL7381627 | 0.78 | NPC1 (0.65) | NPC1TDP1FKBP1APOLBNAAA | |
| SCHEMBL19817236 | 0.78 | NPC1 (0.65) | NPC1TDP1FKBP1APOLBNAAA | |
| SCHEMBL25432319 | 0.78 | NPC1 (0.93) | NPC1TDP1FKBP1APOLBNAAA | |
| SCHEMBL3700679 | 0.78 | NPC1 (1.00) | NPC1TDP1FKBP1APOLBNAAA | |
| SCHEMBL2700497 | 0.77 | NPC1 (0.63) | NPC1TDP1FKBP1APOLBNAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3656782-B1 | PEPTIDE AMIDE COMPOUND AND PREPARATION METHOD AND MEDICAL USE THEREOF | SICHUAN HAISCO PHARMACEUTICAL CO LTD (CN) | 2021-12-22 | — | — | EP | disclosed |
| EP-3656782-A1 | PEPTIDE AMIDE COMPOUND AND PREPARATION METHOD AND MEDICAL USE THEREOF | Sichuan Haisco Pharmaceutical Co., Ltd. (CN) | 2020-05-27 | — | — | EP | disclosed |
| WO-2019015644-A1 | PEPTIDE AMIDE COMPOUND AND PREPARATION METHOD AND MEDICAL USE THEREOF | 四川海思科制药有限公司 | 2019-01-24 | — | — | WO | disclosed |