⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Guanoctine SCHEMBL5909699 | 0.81 | POLB (0.38) | — | |
| SCHEMBL22365664 | 0.81 | — | — | |
| Guanoctine SCHEMBL121121 | 0.79 | POLB (0.37) | — | |
| SCHEMBL27115012 | 0.79 | — | — | |
| SCHEMBL18792696 | 0.77 | POLB (0.32) | — | |
| SCHEMBL25015357 | 0.77 | — | — | |
| SCHEMBL21350057 | 0.77 | — | — | |
| SCHEMBL22511428 | 0.76 | — | — | |
| SCHEMBL18520505 | 0.76 | — | — | |
| SCHEMBL19636411 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |
| US-20200318195-A1 | Bivalent Nucleic Acid Ligands and Uses Therefor | CARNEGIE MELLON UNIVERSITY | 2020-10-08 | — | — | US | disclosed |
| US-20200308220-A1 | AROMATIC-CATIONIC PEPTIDES CONJUGATED TO ANTIOXIDANTS AND THEIR USE IN TREATING COMPLEX REGIONAL PAIN SYNDROME | CLINICAL RESEARCH INSTITUTE OF MONTREAL (CA) | 2020-10-01 | — | — | US | disclosed |
| US-20190276494-A1 | COMPOSITIONS AND METHODS FOR THE PREVENTION AND TREATMENT OF MITOCHONDRIAL MYOPATHIES | STEALTH BIOTHERAPEUTICS INC. | 2019-09-12 | — | — | US | disclosed |
| US-20190022165-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT AND PREVENTION OF PULMONARY ARTERIAL HYPERTENSION | STEALTH BIOTHERAPEUTICS CORP (MC) | 2019-01-24 | — | — | US | disclosed |
| US-20190022167-A1 | METHODS AND COMPOSITIONS FOR THE PREVENTION AND TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | STEALTH BIOTHERAPEUTICS INC. | 2019-01-24 | — | — | US | disclosed |