⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18520505 | 0.83 | — | — | |
| SCHEMBL21743333 | 0.81 | — | — | |
| SCHEMBL25015251 | 0.81 | — | — | |
| SCHEMBL18520678 | 0.81 | — | — | |
| SCHEMBL12458682 | 0.81 | ALDH1A1 (0.31) | — | |
| Guanoctine SCHEMBL5909699 | 0.79 | POLB (0.38) | — | |
| SCHEMBL11416809 | 0.78 | EPHX1 (0.32) | — | |
| Guanoctine SCHEMBL121121 | 0.77 | POLB (0.37) | — | |
| SCHEMBL27115012 | 0.77 | — | — | |
| SCHEMBL20669482 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021202694-A1 | PHENOLIC ACID LIPID BASED CATIONIC LIPIDS | TRANSLATE BIO, INC. (US) | 2021-10-07 | — | — | WO | disclosed |
| WO-2017201433-A1 | COMPOSITIONS AND METHODS FOR THE PREVENTION AND TREATMENT OF MITOCHONDRIAL MYOPATHIES | STEALTH BIOTHERAPEUTICS CORP (MC) | 2017-11-23 | — | — | WO | disclosed |