Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 8/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.46 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 2/20 | 0.44 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.41 |
| ▸ | MMP2 | P08253 | 2/20 | 0.41 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10945464 | 1.00 | GPR84 (0.52) | GPR84FFAR1FFAR4SPHK1FAAH | |
| SCHEMBL10950174 | 1.00 | GPR84 (0.52) | GPR84FFAR1FFAR4SPHK1FAAH | |
| SCHEMBL10951609 | 1.00 | GPR84 (0.52) | GPR84FFAR1FFAR4SPHK1FAAH | |
| SCHEMBL10949074 | 1.00 | GPR84 (0.52) | GPR84FFAR1FFAR4SPHK1FAAH | |
| SCHEMBL10944896 | 1.00 | GPR84 (0.52) | GPR84FFAR1FFAR4SPHK1FAAH | |
| SCHEMBL965223 | 0.88 | GPR84 (0.52) | GPR84FFAR1FFAR4SPHK1FAAH | |
| SCHEMBL6552695 | 0.88 | GPR84 (0.52) | GPR84FFAR1FFAR4SPHK1FAAH | |
| SCHEMBL968429 | 0.88 | GPR84 (0.52) | GPR84FFAR1FFAR4SPHK1FAAH | |
| SCHEMBL967066 | 0.88 | GPR84 (0.52) | GPR84FFAR1FFAR4SPHK1FAAH | |
| SCHEMBL964074 | 0.88 | GPR84 (0.52) | GPR84FFAR1FFAR4SPHK1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019018785-A2 | COMPOSITIONS AND METHODS FOR TREATMENT OF CENTRAL NERVOUS SYSTEM TUMORS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2019-01-24 | — | — | WO | disclosed |