Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 5/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | MPO | P05164 | 1/20 | 0.32 |
| ▸ | HSD17B14 | Q9BPX1 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.30 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.30 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.30 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18463877 | 0.77 | BACE1 (0.50) | BACE1PDE10AHDAC1HDAC2HSD17B14 | |
| SCHEMBL31733680 | 0.70 | BACE1 (0.55) | BACE1HDAC1HDAC2HSD17B14TSHR | |
| Hydrochloric Acid SCHEMBL31733671 | 0.69 | BACE1 (0.53) | BACE1HDAC1HDAC2HSD17B14TSHR | |
| SCHEMBL5180091 | 0.66 | MGAM (0.56) | BACE1HDAC1HDAC2HSD17B14TSHR | |
| SCHEMBL18463775 | 0.66 | KDM4E (0.39) | BACE1PDE10AMPOHSD17B14 | |
| SCHEMBL14339761 | 0.64 | MAPT (0.48) | BACE1HDAC1HDAC2TSHR | |
| SCHEMBL30209650 | 0.62 | BACE1 (0.47) | BACE1PDE10AHDAC1HDAC2 | |
| SCHEMBL9335203 | 0.62 | UNG (0.40) | BACE1HSD17B14 | |
| SCHEMBL14911775 | 0.61 | PDE10A (0.50) | BACE1PDE10AHDAC1HDAC2TSHR | |
| SCHEMBL14352128 | 0.61 | BACE1 (0.55) | BACE1PDE10AHDAC1HDAC2MPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019018562-A1 | AMIDO COMPOUNDS AS AhR MODULATORS | IDEAYA BIOSCIENCES, INC. (US) | 2019-01-24 | — | — | WO | disclosed |