⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18928408 | 0.92 | — | — | |
| SCHEMBL22667748 | 0.92 | — | — | |
| SCHEMBL12834803 | 0.78 | — | — | |
| SCHEMBL12138432 | 0.72 | — | — | |
| SCHEMBL23010816 | 0.72 | — | — | |
| SCHEMBL18813658 | 0.70 | L3MBTL1 (0.31) | — | |
| SCHEMBL19459946 | 0.69 | — | — | |
| SCHEMBL22860598 | 0.69 | — | — | |
| SCHEMBL9766073 | 0.67 | — | — | |
| SCHEMBL24495691 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021073593-A1 | AMINOPYRIMIDINE COMPOUND AS CDK2/4/6 TRIPLE INHIBITOR | 南京明德新药研发有限公司 | 2021-04-22 | — | — | WO | disclosed |
| EP-2358767-B1 | METHOD FOR SEED BED TREATMENT FOR A POLYMERIZATION REACTION | UNIVATION TECH LLC (US) | 2013-02-20 | — | — | EP | disclosed |
| US-8148481-B2 | Method for seed bed treatment for a polymerization reaction | UNIVATION TECHNOLOGIES, LLC (US) | 2012-04-03 | — | — | US | disclosed |
| EP-2358767-A1 | METHOD FOR SEED BED TREATMENT FOR A POLYMERIZATION REACTION | Univation Technologies, LLC (US) | 2011-08-24 | — | — | EP | disclosed |
| WO-2010071798-A1 | METHOD FOR SEED BED TREATMENT FOR A POLYMERIZATION REACTION | UNIVATION TECHNOLOGIES, LLC (US) | 2010-06-24 | — | — | WO | disclosed |
| CN-1200119-A | (METHYLSULFONYL) PHENYL-2- (5H) -FURANONE AS CYCLOOXYGENASE-2 INHIBITORS | MERCK FROSST CANADA INC (CA) | 1998-11-25 | — | — | CN | disclosed |