Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | RARB | P10826 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL390995 | 1.00 | TSHR (0.46) | TSHRCYP3A4MEN1THRBHTT | |
| SCHEMBL5562313 | 0.93 | HTT (0.50) | TSHRCYP3A4MEN1THRBHTT | |
| SCHEMBL11132871 | 0.91 | HTT (0.54) | TSHRCYP3A4MEN1THRBHTT | |
| SCHEMBL3666107 | 0.91 | HTT (0.54) | TSHRCYP3A4MEN1THRBHTT | |
| SCHEMBL3662285 | 0.91 | HTT (0.54) | TSHRCYP3A4MEN1THRBHTT | |
| SCHEMBL3664728 | 0.91 | HTT (0.54) | TSHRCYP3A4MEN1THRBHTT | |
| SCHEMBL3663301 | 0.91 | HTT (0.54) | TSHRCYP3A4MEN1THRBHTT | |
| SCHEMBL5561551 | 0.91 | HTT (0.54) | TSHRCYP3A4MEN1THRBHTT | |
| SCHEMBL5555936 | 0.85 | — | — | |
| SCHEMBL387903 | 0.85 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3200994-B1 | MULTIPLE LAYER INTERLAYER RESISTING DEFECT FORMATION | SOLUTIA INC (US) | 2019-01-30 | — | — | EP | claimed |