Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | THRB | P10828 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | CES2 | O00748 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.37 |
| ▸ | PRKCG | P05129 | 1/20 | 0.37 |
| ▸ | PRKCB | P05771 | 1/20 | 0.37 |
| ▸ | PRKCA | P17252 | 1/20 | 0.37 |
| ▸ | PRKCH | P24723 | 1/20 | 0.37 |
| ▸ | PRKCI | P41743 | 1/20 | 0.37 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.37 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11132871 | 1.00 | HTT (0.54) | HTTTHRBMEN1KMT2AMAPT | |
| SCHEMBL3664728 | 1.00 | HTT (0.54) | HTTTHRBMEN1KMT2AMAPT | |
| SCHEMBL3662285 | 1.00 | HTT (0.54) | HTTTHRBMEN1KMT2AMAPT | |
| SCHEMBL3666107 | 1.00 | HTT (0.54) | HTTTHRBMEN1KMT2AMAPT | |
| SCHEMBL5561551 | 1.00 | HTT (0.54) | HTTTHRBMEN1KMT2AMAPT | |
| SCHEMBL5562313 | 0.98 | HTT (0.50) | HTTTHRBMEN1KMT2AMAPT | |
| SCHEMBL390995 | 0.91 | TSHR (0.46) | HTTTHRBMEN1KMT2AMAPT | |
| SCHEMBL20677347 | 0.91 | TSHR (0.46) | HTTTHRBMEN1KMT2AMAPT | |
| SCHEMBL3665928 | 0.86 | THRB (0.42) | HTTTHRBMEN1KMT2AMAPT | |
| SCHEMBL8778616 | 0.86 | THRB (0.42) | HTTTHRBMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1305322-B1 | DERIVATIVES OF BRANCHED-CHAIN LIPOPHILIC MOLECULES AND USES THEREOF | DPHARM LTD (IL) | 2010-01-13 | — | — | EP | claimed |