Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 10/20 | 0.46 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.39 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20679508 | 1.00 | KCNH2 (0.46) | KCNH2KCNQ1CACNA1C | |
| SCHEMBL20679394 | 0.94 | KCNH2 (0.49) | KCNH2 | |
| SCHEMBL20679446 | 0.94 | KCNH2 (0.49) | KCNH2 | |
| SCHEMBL20679499 | 0.92 | KCNH2 (0.43) | KCNH2 | |
| SCHEMBL20679479 | 0.92 | KCNH2 (0.43) | KCNH2 | |
| SCHEMBL18543810 | 0.92 | KCNH2 (0.51) | KCNH2 | |
| SCHEMBL20687543 | 0.92 | KCNH2 (0.51) | KCNH2 | |
| SCHEMBL18529117 | 0.92 | KCNH2 (0.51) | KCNH2 | |
| SCHEMBL18544221 | 0.92 | KCNH2 (0.51) | KCNH2 | |
| SCHEMBL20679441 | 0.91 | KCNH2 (0.53) | KCNH2KCNQ1CACNA1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10683307-B2 | Compounds for use in antibacterial applications | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2020-06-16 | — | — | US | disclosed |
| US-20190270755-A1 | COMPOUNDS FOR USE IN ANTIBACTERIAL APPLICATIONS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2019-09-05 | — | — | US | disclosed |
| US-10364254-B2 | Compounds for use in antibacterial applications | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2019-07-30 | — | — | US | disclosed |
| US-20190031680-A1 | COMPOUNDS FOR US IN ANTIBACTERIAL APPLICATIONS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2019-01-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10683307-B2 | Compounds for use in antibacterial applications | MRPL21, CFTR, NRDC | KCNH2 2823/4885KCNQ1 2666/4885CACNA1C 4304/4885 |
| US-20190270755-A1 | COMPOUNDS FOR USE IN ANTIBACTERIAL APPLICATIONS | MRPL21, CFTR, NRDC | KCNH2 2823/4885KCNQ1 2666/4885CACNA1C 4304/4885 |
| US-20190031680-A1 | COMPOUNDS FOR US IN ANTIBACTERIAL APPLICATIONS | CFTR, MRPL21, CLPP | KCNH2 2998/4885KCNQ1 3170/4885CACNA1C 4419/4885 |
| US-10364254-B2 | Compounds for use in antibacterial applications | MRPL21, CFTR, NRDC | KCNH2 2823/4885KCNQ1 2666/4885CACNA1C 4304/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.