Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 8/20 | 0.55 |
| ▸ | EGFR | P00533 | 5/20 | 0.52 |
| ▸ | FGFR4 | P22455 | 8/20 | 0.50 |
| ▸ | FGFR2 | P21802 | 5/20 | 0.50 |
| ▸ | SRC | P12931 | 1/20 | 0.50 |
| ▸ | WEE1 | P30291 | 4/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21166354 | 0.87 | FGFR1 (0.60) | FGFR1EGFRFGFR4FGFR2SRC | |
| SCHEMBL16071658 | 0.84 | FGFR1 (0.74) | FGFR1EGFRFGFR4FGFR2 | |
| SCHEMBL16071789 | 0.82 | FGFR1 (0.61) | FGFR1EGFRFGFR4FGFR2SRC | |
| SCHEMBL18895839 | 0.80 | FGFR1 (0.75) | FGFR1EGFRFGFR4FGFR2 | |
| SCHEMBL16071792 | 0.79 | FGFR1 (0.57) | FGFR1EGFRFGFR4FGFR2SRC | |
| SCHEMBL16071655 | 0.77 | FGFR1 (0.81) | FGFR1EGFRFGFR4FGFR2 | |
| SCHEMBL16071654 | 0.76 | FGFR1 (0.77) | FGFR1FGFR4FGFR2 | |
| SCHEMBL16071534 | 0.76 | FGFR1 (0.61) | FGFR1EGFRFGFR4FGFR2SRC | |
| SCHEMBL16071656 | 0.76 | FGFR1 (0.73) | FGFR1EGFRFGFR4FGFR2 | |
| SCHEMBL21860479 | 0.75 | FGFR1 (0.75) | FGFR1EGFRFGFR4FGFR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10189794-B2 | Heteroaryl compounds and uses thereof | CELGENE CAR LLC (BM) | 2019-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10189794-B2 | Heteroaryl compounds and uses thereof | ABCG2, CYP3A43, CYP3A5 | FGFR1 3322/4885EGFR 1981/4885FGFR4 2623/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.