SCHEMBL20683391

SCHEMBL20683391

CC(N)(CCCCB(O)O)CCN1CCCCC1

nearest known ligand 0.63

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ARG1 P05089 19/20 0.63
ARG2 P78540 18/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20683323 0.98 ARG1 (0.62) ARG1ARG2
SCHEMBL20683413 0.95 ARG1 (0.58) ARG1ARG2
SCHEMBL20683354 0.87 ARG1 (0.55) ARG1ARG2
SCHEMBL20683324 0.84 ARG1 (0.52) ARG1ARG2
SCHEMBL20683416 0.82 ARG1 (0.46) ARG1ARG2
SCHEMBL20683321 0.82 ARG1 (0.49) ARG1ARG2
SCHEMBL20683325 0.80 ARG1 (0.49) ARG1ARG2
SCHEMBL20683351 0.80 ARG1 (0.50) ARG1ARG2
SCHEMBL20683401 0.80 ARG1 (0.48) ARG1ARG2
SCHEMBL10207709 0.78 ARG1 (1.00) ARG1ARG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2560978-B1 INHIBITORS OF ARGINASE AND THEIR THERAPEUTIC APPLICATIONS MARS INC (US) 2019-01-30 EP disclosed