Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ARG1 | P05089 | 11/20 | 0.56 |
| ▸ | ARG2 | P78540 | 11/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20683471 | 0.90 | ARG1 (0.67) | ARG1ARG2GRM2GRM3 | |
| SCHEMBL20683465 | 0.89 | ARG1 (0.59) | ARG1ARG2SIGMAR1 | |
| SCHEMBL20683481 | 0.89 | ARG1 (0.56) | ARG1ARG2 | |
| SCHEMBL895591 | 0.89 | ARG1 (0.73) | ARG1ARG2 | |
| SCHEMBL895593 | 0.89 | ARG1 (0.73) | ARG1ARG2 | |
| Hydrochloric Acid SCHEMBL894718 | 0.88 | ARG1 (0.71) | ARG1ARG2 | |
| Hydrochloric Acid SCHEMBL894564 | 0.88 | ARG1 (0.71) | ARG1ARG2 | |
| Hydrochloric Acid SCHEMBL894563 | 0.88 | ARG1 (0.71) | ARG1ARG2 | |
| SCHEMBL20683520 | 0.83 | ARG1 (0.62) | ARG1ARG2SIGMAR1 | |
| SCHEMBL10265155 | 0.83 | ARG1 (0.77) | ARG1ARG2SIGMAR1GRM2GRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2560978-B1 | INHIBITORS OF ARGINASE AND THEIR THERAPEUTIC APPLICATIONS | MARS INC (US) | 2019-01-30 | — | — | EP | disclosed |