Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCNN1A | P37088 | 11/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16443691 | 0.89 | SCNN1A (0.54) | SCNN1AKCNH2 | |
| SCHEMBL16453284 | 0.89 | SCNN1A (0.54) | SCNN1AKCNH2 | |
| SCHEMBL20683800 | 0.89 | SCNN1A (0.54) | SCNN1AKCNH2 | |
| SCHEMBL16443693 | 0.89 | SCNN1A (0.54) | SCNN1AKCNH2 | |
| SCHEMBL16443694 | 0.89 | SCNN1A (0.54) | SCNN1AKCNH2 | |
| Hydrochloric Acid SCHEMBL16443779 | 0.88 | SCNN1A (0.54) | SCNN1AKCNH2 | |
| Hydrochloric Acid SCHEMBL16443778 | 0.88 | SCNN1A (0.54) | SCNN1AKCNH2 | |
| Hydrochloric Acid SCHEMBL16443777 | 0.88 | SCNN1A (0.54) | SCNN1AKCNH2 | |
| SCHEMBL16453195 | 0.88 | SCNN1A (0.49) | SCNN1AKCNH2 | |
| SCHEMBL20683754 | 0.83 | SCNN1A (0.58) | SCNN1AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3030555-B1 | NOVEL PYRAZINE AMIDE COMPOUNDS | BOEHRINGER INGELHEIM INT (DE) | 2019-01-30 | — | — | EP | disclosed |