Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL95157 | 0.88 | TSHR (0.64) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL18506222 | 0.86 | TSHR (0.40) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL9504482 | 0.84 | TSHR (0.55) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL1723604 | 0.82 | TSHR (0.57) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL347559 | 0.82 | TSHR (0.57) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL7212552 | 0.80 | TSHR (0.52) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL8216717 | 0.80 | TSHR (0.52) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL27655410 | 0.80 | TSHR (0.55) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL9656482 | 0.78 | TSHR (0.53) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL3412116 | 0.78 | TSHR (0.53) | TSHRALDH1A1TP53HIF1ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3087111-B1 | PROCESSES TO FORM ETHYLENE-BASED POLYMERS USING ASYMMETRICAL POLYENES | DOW GLOBAL TECHNOLOGIES LLC (US) | 2019-01-30 | — | — | EP | disclosed |