Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.41 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.41 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20686695 | 0.89 | MRGPRX4 (0.44) | MRGPRX4L3MBTL1MAPTRAB9AHPGD | |
| SCHEMBL20686675 | 0.88 | PTGER1 (0.42) | MRGPRX4L3MBTL1MAPTRAB9AHPGD | |
| SCHEMBL20686785 | 0.85 | MRGPRX4 (0.41) | MRGPRX4L3MBTL1MAPTRAB9AHPGD | |
| SCHEMBL20686707 | 0.85 | MRGPRX4 (0.41) | MRGPRX4L3MBTL1MAPTRAB9AHPGD | |
| SCHEMBL20686645 | 0.85 | PTGDR2 (0.40) | MRGPRX4L3MBTL1MAPTRAB9AHPGD | |
| SCHEMBL21317962 | 0.84 | CCR5 (0.41) | MAPTRAB9ANPC1SMN1; SMN2PTGER1 | |
| SCHEMBL20686713 | 0.82 | SMN1; SMN2 (0.45) | MAPTRAB9ANPC1SMN1; SMN2KDM4E | |
| SCHEMBL16920896 | 0.81 | MRGPRX4 (0.50) | MRGPRX4L3MBTL1MAPTRAB9AHPGD | |
| SCHEMBL20686696 | 0.78 | MRGPRX4 (0.44) | MRGPRX4L3MBTL1MAPTRAB9AHPGD | |
| SCHEMBL18749360 | 0.78 | MRGPRX4 (0.49) | MRGPRX4L3MBTL1MAPTRAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2940012-B1 | TETRAZOLINONE COMPOUND AND APPLICATIONS THEREOF | SUMITOMO CHEMICAL CO (JP) | 2019-01-30 | — | — | EP | disclosed |