Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 11/20 | 0.53 |
| ▸ | PIK3CA | P42336 | 10/20 | 0.53 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.52 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.48 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 4/20 | 0.37 |
| ▸ | USP2 | O75604 | 3/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.36 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17047563 | 0.86 | PIK3CG (0.67) | PIK3CGPIK3CAPIK3CDPIK3CBDYRK1A | |
| SCHEMBL17047520 | 0.83 | PIK3CG (0.67) | PIK3CGPIK3CAPIK3CDPIK3CBDYRK1A | |
| SCHEMBL23349770 | 0.72 | ALOX5 (0.45) | PIK3CDPIK3CBALDH1A1TSHRMAPT | |
| SCHEMBL17047554 | 0.71 | PIK3CG (1.00) | PIK3CGPIK3CAPIK3CDPIK3CBALDH1A1 | |
| SCHEMBL24217373 | 0.71 | ALOX5 (0.47) | PIK3CGPIK3CAPIK3CDPIK3CBALDH1A1 | |
| SCHEMBL23349535 | 0.70 | ALOX5 (0.43) | PIK3CGPIK3CAPIK3CDPIK3CBALDH1A1 | |
| SCHEMBL23349509 | 0.70 | ALOX5 (0.42) | PIK3CGPIK3CAPIK3CDPIK3CBALDH1A1 | |
| SCHEMBL17047463 | 0.70 | PIK3CG (0.77) | PIK3CGPIK3CAPIK3CDPIK3CBALDH1A1 | |
| SCHEMBL23349771 | 0.70 | ALOX5 (0.46) | PIK3CGPIK3CAPIK3CDPIK3CBALDH1A1 | |
| SCHEMBL26712304 | 0.70 | ALOX5 (0.41) | PIK3CGPIK3CAPIK3CDPIK3CBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3110801-B1 | 6-ARYL-4-PHENYLAMINO-QUINAZOLINE ANALOGS AS PHOSPHOINOSITIDE-3-KINASE INHIBITORS | COUNCIL SCIENT IND RES (IN) | 2019-01-30 | — | — | EP | disclosed |