Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 20/20 | 0.80 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21726366 | 1.00 | TYK2 (0.80) | TYK2PDE4D | |
| SCHEMBL21726416 | 0.91 | TYK2 (0.76) | TYK2 | |
| SCHEMBL20687734 | 0.90 | TYK2 (0.85) | TYK2PDE4D | |
| SCHEMBL21755327 | 0.89 | TYK2 (1.00) | TYK2PDE4D | |
| SCHEMBL20688316 | 0.89 | TYK2 (1.00) | TYK2PDE4D | |
| SCHEMBL29990561 | 0.89 | TYK2 (1.00) | TYK2PDE4D | |
| SCHEMBL29991106 | 0.88 | TYK2 (0.81) | TYK2PDE4D | |
| SCHEMBL21726423 | 0.86 | TYK2 (0.77) | TYK2PDE4D | |
| SCHEMBL20696808 | 0.83 | TYK2 (0.87) | TYK2PDE4D | |
| SCHEMBL20678843 | 0.83 | TYK2 (0.87) | TYK2PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019023468-A1 | TYK2 INHIBITORS AND USES THEREOF | NIMBUS LAKSHMI, INC. (US) | 2019-01-31 | — | — | WO | disclosed |