Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 20/20 | 1.00 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20688316 | 1.00 | TYK2 (1.00) | TYK2PDE4D | |
| SCHEMBL29990561 | 1.00 | TYK2 (1.00) | TYK2PDE4D | |
| SCHEMBL20687734 | 0.92 | TYK2 (0.85) | TYK2PDE4D | |
| SCHEMBL20689083 | 0.92 | TYK2 (1.00) | TYK2PDE4D | |
| SCHEMBL29991106 | 0.89 | TYK2 (0.81) | TYK2PDE4D | |
| SCHEMBL20688959 | 0.89 | TYK2 (0.80) | TYK2PDE4D | |
| SCHEMBL21726366 | 0.89 | TYK2 (0.80) | TYK2PDE4D | |
| SCHEMBL20688285 | 0.85 | TYK2 (1.00) | TYK2PDE4D | |
| SCHEMBL20688252 | 0.85 | TYK2 (0.92) | TYK2 | |
| SCHEMBL20687910 | 0.84 | TYK2 (0.87) | TYK2PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10570145-B2 | TYK2 inhibitors and uses thereof | Nimbus Lakshimi, Inc. (US) | 2020-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10570145-B2 | TYK2 inhibitors and uses thereof | TYK2, JAK2, JAK1 | TYK2 1/4885PDE4D 4496/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.