Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 3/20 | 0.42 |
| ▸ | PGR | P06401 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.39 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | IMPDH2 | P12268 | 3/20 | 0.35 |
| ▸ | IMPDH1 | P20839 | 2/20 | 0.35 |
| ▸ | MDM4 | O15151 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.34 |
| ▸ | ANPEP | P15144 | 1/20 | 0.34 |
| ▸ | UPP1 | Q16831 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12310191 | 0.97 | AR (0.41) | ARPGRKDM4EALDH1A1GAA | |
| SCHEMBL31399295 | 0.84 | TSHR (0.39) | ARPGRKDM4EALDH1A1GAA | |
| SCHEMBL152358 | 0.84 | TSHR (0.39) | ARPGRKDM4EALDH1A1GAA | |
| SCHEMBL5250992 | 0.81 | CYP1A2 (0.50) | ARPGRKDM4EALDH1A1GAA | |
| SCHEMBL28241231 | 0.81 | ANPEP (0.56) | ARKDM4EALDH1A1GAAMAPT | |
| SCHEMBL5250990 | 0.81 | ALDH1A1 (0.41) | ARPGRKDM4EALDH1A1GAA | |
| SCHEMBL8828836 | 0.81 | ANPEP (0.56) | ARKDM4EALDH1A1GAAMAPT | |
| SCHEMBL27829855 | 0.81 | DYRK1A (0.47) | ARPGRKDM4EALDH1A1GAA | |
| SCHEMBL7302562 | 0.81 | CA1 (0.39) | ARPGRKDM4EALDH1A1GAA | |
| SCHEMBL820788 | 0.78 | AR (0.34) | ARPGRESR1ESR2IMPDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190031671-A1 | SYNTHESIS OF A 1,2,5,6-NAPHTHALENEDIIMIDE MONOMER | PHILLIPS 66 COMPANY (US) | 2019-01-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190031671-A1 | SYNTHESIS OF A 1,2,5,6-NAPHTHALENEDIIMIDE MONOMER | NDC1, NUCB2, NOC2L | AR 1050/4885PGR 3063/4885KDM4E 3341/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.