Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNASEL | Q05823 | 1/20 | 0.45 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.45 |
| ▸ | P2RY11 | Q96G91 | 2/20 | 0.45 |
| ▸ | AHCY | P23526 | 1/20 | 0.43 |
| ▸ | P2RY1 | P47900 | 4/20 | 0.43 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.43 |
| ▸ | SRC | P12931 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.43 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.43 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.43 |
| ▸ | LDHA | P00338 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | FBP1 | P09467 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.43 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24681145 | 0.85 | RNASEL (0.38) | RNASELENPP1P2RY11 | |
| SCHEMBL24681007 | 0.81 | BCHE (0.51) | ENPP1P2RY11P2RY1P2RY2SRC | |
| SCHEMBL12963431 | 0.79 | ENPP1 (0.64) | ENPP1P2RY11P2RY1P2RY2SRC | |
| SCHEMBL7745726 | 0.77 | ADORA1 (0.64) | RNASELP2RY11P2RY1P2RY2SRC | |
| SCHEMBL14064192 | 0.76 | POLB (0.55) | ENPP1P2RY11P2RY1P2RY2SRC | |
| SCHEMBL19153626 | 0.76 | P2RY1 (0.57) | P2RY11P2RY1P2RY2SRCSMN1; SMN2 | |
| SCHEMBL20763281 | 0.76 | P2RY1 (0.63) | RNASELP2RY11P2RY1P2RY2SRC | |
| SCHEMBL20691945 | 0.76 | BCHE (0.50) | ENPP1P2RY11P2RY1P2RY2SRC | |
| SCHEMBL20691455 | 0.76 | BCHE (0.50) | ENPP1P2RY11P2RY1P2RY2SRC | |
| SCHEMBL20692152 | 0.75 | RNASEL (0.57) | RNASELP2RY1P2RY2SRCP2RX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3658565-B1 | CYCLIC DINUCLEOTIDES AS ANTICANCER AGENTS | BRISTOL MYERS SQUIBB CO (US) | 2022-11-09 | — | — | EP | disclosed |
| WO-2019023459-A1 | CYCLIC DINUCLEOTIDES AS ANTICANCER AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2019-01-31 | — | — | WO | disclosed |