Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 16/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CDC25B | P30305 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29775276 | 0.92 | ACHE (0.56) | ACHEKDM4EMEN1ALDH1A1GAA | |
| SCHEMBL865194 | 0.92 | ACHE (0.56) | ACHEKDM4EMEN1ALDH1A1GAA | |
| SCHEMBL24784456 | 0.92 | ACHE (0.56) | ACHEKDM4EMEN1ALDH1A1GAA | |
| SCHEMBL410953 | 0.92 | ACHE (0.56) | ACHEKDM4EMEN1ALDH1A1GAA | |
| SCHEMBL8255700 | 0.86 | ACHE (0.58) | ACHEKDM4EMEN1ALDH1A1GAA | |
| SCHEMBL18009557 | 0.81 | ACHE (0.53) | ACHEKDM4EMEN1ALDH1A1GAA | |
| SCHEMBL8990233 | 0.81 | ACHE (0.64) | ACHEKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL8091521 | 0.79 | ACHE (0.69) | ACHEKDM4EMEN1ALDH1A1GAA | |
| SCHEMBL29621066 | 0.79 | ACHE (0.61) | ACHEKDM4EMEN1ALDH1A1GAA | |
| SCHEMBL8099829 | 0.79 | ACHE (0.69) | ACHEKDM4EMEN1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020102576-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | NOVARTIS INFLAMMASOME RESEARCH, INC. (US) | 2020-05-22 | — | — | WO | disclosed |
| WO-2020102574-A1 | THE COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | NOVARTIS INFLAMMASOME RESEARCH, INC. (US) | 2020-05-22 | — | — | WO | disclosed |
| WO-2019023147-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | IFM Tre, Inc. (US) | 2019-01-31 | — | — | WO | disclosed |