SCHEMBL20693292

SCHEMBL20693292

C=CC(=O)OCCCCOc1ccc(C(=O)OC2=CC=C(OC(=O)c3ccc(OC(=O)NCCOC(=O)C(=C)C)cc3)CC2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.47
POLB P06746 1/20 0.47
APEX1 P27695 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
MGLL Q99685 1/20 0.37
NPC1 O15118 2/20 0.36
LMNA P02545 2/20 0.36
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
NFKB1 P19838 1/20 0.35
NFKB2 Q00653 1/20 0.35
RELA Q04206 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
THRB P10828 1/20 0.35
TSHR P16473 2/20 0.34
USP2 O75604 1/20 0.34
ALOX15 P16050 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20693242 0.99 HTT (0.46) HTTPOLBAPEX1TDP1MGLL
SCHEMBL16885041 0.93 HTT (0.52) HTTPOLBAPEX1TDP1MGLL
SCHEMBL21883828 0.93 MGLL (0.40) HTTPOLBAPEX1TDP1MGLL
SCHEMBL20693221 0.92 MGLL (0.39) HTTPOLBMGLLNPC1LMNA
SCHEMBL21883934 0.91 MGLL (0.39) HTTPOLBAPEX1TDP1MGLL
SCHEMBL16885054 0.91 POLB (0.49) HTTPOLBAPEX1TDP1MGLL
SCHEMBL20693251 0.89 HTT (0.52) HTTPOLBAPEX1TDP1NPC1
SCHEMBL20693245 0.88 HTT (0.51) HTTPOLBAPEX1TDP1NPC1
SCHEMBL16885172 0.86 POLB (0.43) HTTPOLBAPEX1TDP1MGLL
SCHEMBL16885166 0.86 POLB (0.59) HTTPOLBAPEX1TDP1MGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11634638-B2 Liquid crystal composition, reflective layer, method for producing reflective layer, and copolymer FUJIFILM CORPORATION (JP) 2023-04-25 US disclosed
US-11332671-B2 Liquid crystal composition, method for producing reflective layer, reflective layer, cured product, and optically anisotropic body FUJIFILM CORPORATION (JP) 2022-05-17 US disclosed
US-11209688-B2 Reflective layer obtained by immobilizing cholesteric liquid crystalline phase FUJIFILM CORPORATION (JP) 2021-12-28 US disclosed
US-10942438-B2 Structure and method of manufacturing structure FUJIFILM CORPORATION (JP) 2021-03-09 US disclosed
US-20200231874-A1 LIQUID CRYSTAL COMPOSITION, REFLECTIVE LAYER, METHOD FOR PRODUCING REFLECTIVE LAYER, AND COPOLYMER FUJIFILM CORPORATION (JP) 2020-07-23 US disclosed
US-20200102500-A1 LIQUID CRYSTAL COMPOSITION, METHOD FOR PRODUCING REFLECTIVE LAYER, REFLECTIVE LAYER, CURED PRODUCT, AND OPTICALLY ANISOTROPIC BODY FUJIFILM CORPORATION (JP) 2020-04-02 US disclosed
US-20190033634-A1 METHOD FOR PRODUCING REFLECTIVE LAYER AND REFLECTIVE LAYER FUJIFILM CORPORATION (JP) 2019-01-31 US disclosed