Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.50 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | BPTF | Q12830 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.44 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3576601 | 0.89 | LMNA (0.57) | LMNANCOA1NCOA3KMT2AKDM4E | |
| SCHEMBL17655659 | 0.89 | TPMT (0.53) | LMNAKMT2AKDM4EMEN1ALDH1A1 | |
| SCHEMBL8639986 | 0.85 | BPTF (0.56) | KMT2AKDM4EMEN1ALDH1A1TSHR | |
| SCHEMBL28030473 | 0.84 | TSHR (0.66) | LMNAKMT2AMEN1ALDH1A1TSHR | |
| SCHEMBL24161921 | 0.83 | TPMT (0.60) | LMNAKMT2AKDM4EMEN1ALDH1A1 | |
| SCHEMBL19272078 | 0.83 | LMNA (0.53) | LMNAKMT2AKDM4EMEN1ALDH1A1 | |
| SCHEMBL19351166 | 0.83 | HSD17B2 (0.58) | KMT2AKDM4EMEN1ALDH1A1TSHR | |
| SCHEMBL20693295 | 0.82 | TSHR (0.48) | LMNAKMT2AKDM4EALDH1A1TSHR | |
| SCHEMBL24161920 | 0.81 | CYP3A4 (0.47) | KMT2AKDM4EMEN1ALDH1A1TSHR | |
| Methyl Syringate SCHEMBL211747 | 0.80 | MEN1 (0.61) | KMT2AKDM4EMEN1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190032098-A1 | PROCESS FOR PREPARING BIPHENYL COMPOUNDS | UNIV BORDEAUX (FR) | 2019-01-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190032098-A1 | PROCESS FOR PREPARING BIPHENYL COMPOUNDS | CYP1B1, CYP1A1, CYP1A2 | LMNA 1727/4885NCOA1 2419/4885NCOA3 3113/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.