Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R2 | Q9NPC1 | 14/20 | 0.60 |
| ▸ | AGTR1 | P30556 | 8/20 | 0.59 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.59 |
| ▸ | GP6 | Q9HCN6 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21097873 | 0.90 | LTB4R2 (0.54) | LTB4R2AGTR1ABCB11GP6 | |
| SCHEMBL21098339 | 0.90 | LTB4R2 (0.54) | LTB4R2AGTR1ABCB11GP6 | |
| SCHEMBL19236573 | 0.88 | LTB4R2 (0.60) | LTB4R2AGTR1ABCB11GP6 | |
| SCHEMBL21098639 | 0.87 | LTB4R2 (0.56) | LTB4R2AGTR1ABCB11GP6 | |
| SCHEMBL25964113 | 0.86 | LTB4R2 (0.66) | LTB4R2AGTR1ABCB11GP6 | |
| SCHEMBL2364 | 0.86 | LTB4R2 (0.80) | LTB4R2AGTR1ABCB11GP6 | |
| SCHEMBL2365 | 0.86 | LTB4R2 (0.80) | LTB4R2AGTR1ABCB11GP6 | |
| SCHEMBL18406103 | 0.86 | LTB4R2 (0.60) | LTB4R2AGTR1ABCB11GP6 | |
| SCHEMBL19342800 | 0.85 | LTB4R2 (0.63) | LTB4R2AGTR1ABCB11GP6 | |
| SCHEMBL17946059 | 0.85 | LTB4R2 (0.69) | LTB4R2AGTR1ABCB11GP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021221521-A1 | A SOLID CO-AMORPHOUS DISPERSION OF VALSARTAN, A METHOD FOR SYNTHETIZING THE SAME AND A MEDICAL USE OF THE DISPERSION | UNIWERSYTET HUMANISTYCZNO-PRZYRODNICZY IM JANA DLUGOSZA W CZESTOCHOWIE (PL) | 2021-11-04 | — | — | WO | disclosed |
| EP-3658122-B1 | PHARMACEUTICAL COMPOSITION COMPRISING SACUBITRIL AND VALSARTAN | SYNTHON BV (NL) | 2021-04-07 | — | — | EP | disclosed |
| EP-3250565-B1 | TETRAZOLONES AS CARBOXYLIC ACID BIOISOSTERES | RIGEL PHARMACEUTICALS INC (US) | 2019-07-03 | — | — | EP | disclosed |
| WO-2019020706-A1 | PHARMACEUTICAL COMPOSITION COMPRISING SACUBITRIL AND VALSARTAN | SYNTHON B.V. (NL) | 2019-01-31 | — | — | WO | disclosed |