Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.68 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.53 |
| ▸ | CNR1 | P21554 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3915490 | 0.81 | IDO1 (1.00) | IDO1TAAR1CYP2C19CYP1A2CYP2D6 | |
| SCHEMBL10310268 | 0.81 | IDO1 (0.68) | IDO1TAAR1CYP2C19CYP1A2CYP2D6 | |
| SCHEMBL8581580 | 0.81 | IDO1 (0.68) | IDO1TAAR1CYP2C19CYP1A2CYP2D6 | |
| SCHEMBL10731587 | 0.80 | NPC1 (0.59) | IDO1TAAR1CYP2C19CYP1A2CYP2D6 | |
| SCHEMBL20000816 | 0.77 | CA12 (0.49) | IDO1KMT2ALMNAGAAPOLB | |
| SCHEMBL6885865 | 0.76 | KMT2A (0.75) | IDO1KMT2ALMNAGAAMAPT | |
| SCHEMBL8441620 | 0.75 | IDO1 (0.60) | IDO1TAAR1CYP2C19CYP1A2CYP2D6 | |
| SCHEMBL4582082 | 0.74 | TAAR1 (0.65) | IDO1TAAR1CYP2C19CYP1A2CYP2D6 | |
| SCHEMBL1223474 | 0.74 | CNR1 (0.68) | IDO1TAAR1CYP2C19CYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL19371410 | 0.74 | IDO1 (0.58) | IDO1TAAR1CYP2C19CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190031628-A1 | AMINOAZOLE DERIVATIVE | TEIJIN PHARMA LIMITED (JP) | 2019-01-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190031628-A1 | AMINOAZOLE DERIVATIVE | AR, NR3C2, NR5A1 | IDO1 2443/4885TAAR1 85/4885CYP2C19 963/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.