SCHEMBL2069655

SCHEMBL2069655

N#CCC1(C#N)CCCCC1

nearest known ligand 0.40

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3495531 1.00 ALDH1A1 (0.40) ALDH1A1
SCHEMBL3494205 0.97 ALDH1A1 (0.36) ALDH1A1
SCHEMBL1504251 0.92
SCHEMBL25338300 0.86
SCHEMBL29269115 0.80 ALDH1A1 (0.37) ALDH1A1
SCHEMBL2154404 0.78 ALDH1A1 (0.43) ALDH1A1
SCHEMBL2154595 0.78 ALDH1A1 (0.43) ALDH1A1
SCHEMBL17077903 0.77
SCHEMBL5346809 0.74 ALDH1A1 (0.40) ALDH1A1
SCHEMBL10616514 0.74 ALDH1A1 (0.40) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 166 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12428656-B2 Nitrilase mutant and application thereof in the synthesis of 1-cyanocyclohexyl acetic acid ZHEJIANG UNIVERSITY OF TECHNOLOGY (CN) 2025-09-30 US claimed
WO-2025062312-A1 ONE-POT PROCESS FOR THE PREPARATION OF GABAPENTIN INTERMEDIATE GRANULES INDIA LIMITED (IN) 2025-03-27 WO claimed
US-20250084395-A1 ENGINEERED NITRILASES FOR BIOCATALYSIS KCAT ENZYMATIC PRIVATE LIMITED (IN) 2025-03-13 US claimed
WO-2025041039-A1 IMMOBILISED WHOLE CELL NITRILASES FOR BIOCATALYSIS OF GABAPENTIN INTERMEDIATE GRANULES INDIA LIMITED (IN) 2025-02-27 WO claimed
CN-119193553-A Nitrilase mutant containing unnatural amino acid, coding gene, recombinant vector, recombinant strain and application thereof 浙江工业大学 2024-12-27 CN claimed
CN-118440142-A Connecting peptide, nitrilase fusion protein and application thereof 浙江工业大学 2024-08-06 CN claimed
US-11987826-B2 Nitrilase mutant and application thereof in the synthesis of an anti-epileptic drug intermediate ZHEJIANG UNIVERSITY OF TECHNOLOGY (CN) 2024-05-21 US claimed
CN-114958801-B Product tolerant nitrilase mutant and application thereof 浙江工业大学 2024-05-03 CN claimed
CN-117848995-A Method for monitoring enzymatic reaction of amide substances, on-line monitoring and automatic control equipment 北京衍微科技有限公司 2024-04-09 CN claimed
CN-117825323-A Modeling method for monitoring content change of each component in amide substance production process 北京衍微科技有限公司 2024-04-05 CN claimed
US-20130288315-A1 Nitrilases C-LECTA GMBH (DE) 2013-10-31 US claimed
EP-2627666-A2 NITRILASES WITH IMPROVED ACTIVITY c-LEcta GmbH (DE) 2013-08-21 EP claimed
WO-2012048865-A2 NITRILASES C-LECTA GMBH (DE) 2012-04-19 WO claimed
EP-1639118-A1 BIOCATALYTIC PREPARATION OF 1-CYANOCYCLOHEXANEACETIC ACID Pfizer Products Inc. (US) 2006-03-29 EP claimed
US-20050009154-A1 Biocatalytic preparation of 1-cyano-cyclohexaneacetic acid PFIZER INC 2005-01-13 US claimed
WO-2004111256-A1 BIOCATALYTIC PREPARATION OF 1-CYANOCYCLOHEXANEACETIC ACID PFIZER PRODUCTS INC. (US) 2004-12-23 WO claimed
EP-0432504-B1 Process for preparing 1-(aminomethyl)cyclohexane acetic acid LONZA AG (CH) 1994-06-08 EP claimed
US-5149870-A Process for the production of 1-(aminomethyl)cyclohexane acetic acid LONZA LTD. (CH) 1992-09-22 US claimed
US-5136091-A Alcoholysis, hydrolysis, transesterification, and hydrogenatio hydrogenation; acid & basic catalysts; anticonvulsants LONZA LTD. (CH) 1992-08-04 US claimed
EP-0432504-A1 Process for preparing 1-(aminomethyl)cyclohexane acetic acid LONZA AG (CH) 1991-06-19 EP claimed