Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | MAT2A | P31153 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.42 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.42 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.40 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GRM1 | Q13255 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | EP300 | Q09472 | 1/20 | 0.37 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21285312 | 0.84 | CYP3A4 (0.45) | ELANEMAT2ACYP3A4CYP2A6CYP2E1 | |
| SCHEMBL20687686 | 0.80 | CYP3A4 (0.42) | ELANECYP3A4CYP2A6CYP2E1HTT | |
| SCHEMBL21258570 | 0.77 | RXFP1 (0.44) | MEN1USP2CASP1CASP7KMT2A | |
| SCHEMBL2692307 | 0.76 | MAT2A (0.41) | ELANEMAT2ACYP3A4CYP2A6CYP2E1 | |
| SCHEMBL21246043 | 0.76 | POLB (0.44) | MEN1USP2CASP1BRCA1CASP7 | |
| SCHEMBL31456729 | 0.75 | CYP2A6 (0.53) | ELANECYP3A4CYP2A6CYP2E1HTT | |
| Hydrochloric Acid SCHEMBL15346752 | 0.75 | MAT2A (0.40) | ELANEMAT2ACYP3A4CYP2A6CYP2E1 | |
| Ammonia Solution, Strong SCHEMBL20569938 | 0.75 | MAT2A (0.40) | ELANEMAT2ACYP3A4CYP2A6CYP2E1 | |
| Hydrochloric Acid SCHEMBL2688884 | 0.75 | MAT2A (0.40) | ELANEMAT2ACYP3A4CYP2A6CYP2E1 | |
| SCHEMBL21285306 | 0.75 | TYK2 (0.42) | MEN1USP2CASP1BRCA1CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11046698-B2 | TYK2 inhibitors and uses thereof | NIMBUS LAKSHMI, INC. (US) | 2021-06-29 | — | — | US | disclosed |
| US-20190031664-A1 | TYK2 INHIBITORS AND USES THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2019-01-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11046698-B2 | TYK2 inhibitors and uses thereof | TYK2, JAK2, JAK1 | ELANE 4836/4885MAT2A 1724/4885CYP3A4 4404/4885 |
| US-20190031664-A1 | TYK2 INHIBITORS AND USES THEREOF | TYK2, JAK2, JAK1 | ELANE 4836/4885MAT2A 1724/4885CYP3A4 4404/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.