Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 7/20 | 0.41 |
| ▸ | PDE2A | O00408 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | GRM8 | O00222 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.36 |
| ▸ | GABRP | O00591 | 1/20 | 0.35 |
| ▸ | GABRD | O14764 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20697994 | 0.92 | FGFR1 (0.48) | FGFR1PDE2APDE10AALDH1A1MAPT | |
| SCHEMBL20697990 | 0.91 | FGFR1 (0.39) | FGFR1PDE2APDE10AALDH1A1MAPT | |
| SCHEMBL20697997 | 0.89 | FGFR1 (0.40) | FGFR1PDE2APDE10AALDH1A1MAPT | |
| SCHEMBL20698301 | 0.89 | SIK1 (0.41) | FGFR1PDE2APDE10AALDH1A1MAPT | |
| SCHEMBL20698025 | 0.88 | FGFR1 (0.44) | FGFR1PDE2APDE10AALDH1A1MAPT | |
| SCHEMBL20698120 | 0.88 | GRM8 (0.41) | FGFR1PDE2APDE10AALDH1A1MAPT | |
| SCHEMBL20698168 | 0.87 | FGFR1 (0.41) | FGFR1PDE2APDE10AALDH1A1MAPT | |
| SCHEMBL20698162 | 0.86 | PTGS2 (0.42) | FGFR1PDE2APDE10AALDH1A1MAPT | |
| SCHEMBL20698298 | 0.85 | FGFR1 (0.38) | FGFR1PDE2APDE10AALDH1A1MAPT | |
| SCHEMBL20698167 | 0.85 | HTT (0.39) | FGFR1PDE2APDE10AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019020981-A1 | PYRAZOLE, ISOTHIAZOLE AND ISOXAZOLE DERIVATIVES USEFUL AS AGRICULTURAL FUNGICIDES | REDAG CROP PROTECTION LTD. (GB) | 2019-01-31 | — | — | WO | disclosed |