Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 7/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.38 |
| ▸ | PRPS1 | P60891 | 1/20 | 0.38 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21187466 | 0.81 | DPP4 (0.47) | DPP4DPP8MAPK1NPSR1 | |
| SCHEMBL24807695 | 0.79 | DPP4 (0.39) | DPP4DPP8NPC1RAB9ATP53 | |
| SCHEMBL20698154 | 0.78 | PRPS1 (0.41) | DPP4DPP8PRPS1MAPK1 | |
| SCHEMBL25053031 | 0.78 | DPP4 (0.41) | DPP4DPP8 | |
| SCHEMBL24463625 | 0.78 | DPP4 (0.38) | DPP4DPP8 | |
| SCHEMBL11586303 | 0.78 | DPP4 (0.42) | DPP4DPP8NPC1RAB9AGFER | |
| SCHEMBL31257412 | 0.78 | ESR1 (0.38) | DPP4DPP8 | |
| Hydrochloric Acid SCHEMBL30071608 | 0.76 | DPP4 (0.40) | DPP4DPP8 | |
| SCHEMBL24943956 | 0.75 | DPP4 (0.37) | DPP4MAPK1 | |
| SCHEMBL20698153 | 0.75 | DPP4 (0.37) | DPP4GFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019020981-A1 | PYRAZOLE, ISOTHIAZOLE AND ISOXAZOLE DERIVATIVES USEFUL AS AGRICULTURAL FUNGICIDES | REDAG CROP PROTECTION LTD. (GB) | 2019-01-31 | — | — | WO | disclosed |