SCHEMBL20698607

SCHEMBL20698607

CC1(C)CCN1CCCOS

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CD274 Q9NZQ7 1/20 0.32
SLC29A1 Q99808 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24114465 0.89 SLC29A1 (0.30) SLC29A1
SCHEMBL24114555 0.87 HRH3 (0.31)
SCHEMBL22820873 0.82 CD274 (0.33) CD274SLC29A1
SCHEMBL21376985 0.78 CD274 (0.32) CD274
SCHEMBL20980937 0.77 CD274 (0.31) CD274
SCHEMBL20698400 0.76 CD274 (0.31) CD274
SCHEMBL23713760 0.73
SCHEMBL22820872 0.72
SCHEMBL21792999 0.71 ALDH1A1 (0.32) SLC29A1
SCHEMBL21793001 0.69 HRH3 (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3658522-B1 IMMUNOMODULATOR COMPOUNDS CHEMOCENTRYX INC (US) 2021-12-22 EP disclosed
WO-2020047035-A1 METHODS OF TREATING CANCER WITH SMALL MOLECULE PD-L1 INHIBITORS CHEMOCENTRYX, INC. (US) 2020-03-05 WO disclosed
WO-2019023575-A1 IMMUNOMODULATOR COMPOUNDS CHEMOCENTRYX, INC. (US) 2019-01-31 WO disclosed