SCHEMBL20698644

SCHEMBL20698644

c1cc(-c2ccc3sc4ccccc4c3c2)cc(-c2ccc3ccc4c(-c5ccc6c(c5)oc5ccc(-c7ccc(-c8ccc9ccc%10ccc%11ccccc%11c%10c9c8)cc7)cc56)cc5ccccc5c4c3c2)c1

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRKDC P78527 1/20 0.33
CYP1A1 P04798 1/20 0.32
CYP1A2 P05177 1/20 0.32
FYN P06241 1/20 0.32
MAPK3 P27361 1/20 0.32
AHR P35869 1/20 0.32
PAX8 Q06710 1/20 0.32
ABCG2 Q9UNQ0 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
MAPK1 P28482 1/20 0.31
KMT2A Q03164 1/20 0.31
KDM4E B2RXH2 1/20 0.30
ALDH1A1 P00352 1/20 0.30
MAPT P10636 1/20 0.30
HPGD P15428 1/20 0.30
ALOX15 P16050 1/20 0.30
TSHR P16473 1/20 0.30
CASP1 P29466 1/20 0.30
CASP7 P55210 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20698538 0.88 ERBB2 (0.32) PRKDCCYP1A2FYNAHR
SCHEMBL20698490 0.85 ABCG2 (0.38) CYP1A1CYP1A2FYNMAPK3AHR
SCHEMBL26435527 0.82 KMT2A (0.33) CYP1A1CYP1A2FYNMAPK3AHR
SCHEMBL17692088 0.81 NQO2 (0.41) CYP1A1CYP1A2FYNAHRTDP1
SCHEMBL17692100 0.80 NQO2 (0.39) CYP1A1CYP1A2FYNAHRTDP1
SCHEMBL17692110 0.80 GPR3 (0.42) CYP1A1CYP1A2FYNAHRALDH1A1
SCHEMBL24171039 0.79 PRKDC (0.41) PRKDCAHRKMT2AKDM4EALDH1A1
SCHEMBL26193621 0.79 PRKDC (0.37) PRKDCCYP1A2L3MBTL1PLA2G10PLA2G2A
SCHEMBL24991416 0.79 TDP1 (0.36) PRKDCTDP1L3MBTL1
SCHEMBL21180552 0.79 TDP1 (0.44) CYP1A1CYP1A2FYNMAPK3AHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190036043-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2019-01-31 US disclosed