Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30796460 | 1.00 | GRM4 (0.53) | GRM4ALDH1A1HPGDTSHRFFAR1 | |
| SCHEMBL2072536 | 0.99 | GRM4 (0.51) | GRM4ALDH1A1HPGDTSHRFFAR1 | |
| SCHEMBL30795472 | 0.99 | GRM4 (0.51) | GRM4ALDH1A1HPGDTSHRFFAR1 | |
| SCHEMBL2069782 | 0.97 | GRM4 (0.48) | GRM4ALDH1A1HPGDTSHRFFAR1 | |
| SCHEMBL30795247 | 0.97 | GRM4 (0.48) | GRM4ALDH1A1HPGDTSHRFFAR1 | |
| SCHEMBL30795548 | 0.96 | FFAR1 (0.47) | GRM4ALDH1A1HPGDFFAR1KMT2A | |
| SCHEMBL2071661 | 0.96 | FFAR1 (0.47) | GRM4ALDH1A1HPGDFFAR1KMT2A | |
| SCHEMBL2072782 | 0.83 | ALDH1A1 (0.45) | ALDH1A1HPGDFFAR1KMT2ASMN1; SMN2 | |
| SCHEMBL30794649 | 0.83 | ALDH1A1 (0.45) | ALDH1A1HPGDFFAR1KMT2ASMN1; SMN2 | |
| SCHEMBL27749622 | 0.81 | FFAR1 (0.54) | ALDH1A1FFAR1KMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7906537-B2 | Substituted p-diaminobenzene derivatives | H. LUNDBECK A/S (DK) | 2011-03-15 | — | — | US | disclosed |