SCHEMBL2070118

SCHEMBL2070118

CCCCCSc1ccccc1O

nearest known ligand 0.62

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 1/20 0.62
PTGS2 P35354 4/20 0.55
CYSLTR2 Q9NS75 1/20 0.48
CYSLTR1 Q9Y271 1/20 0.48
P4HB P07237 1/20 0.46
NAAA Q02083 1/20 0.42
SOAT1 P35610 9/20 0.41
HPGD P15428 1/20 0.41
TLR8 Q9NR97 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22444760 0.98 EPHX2 (0.64) EPHX2PTGS2CYSLTR2CYSLTR1P4HB
SCHEMBL9447706 0.98 EPHX2 (0.64) EPHX2PTGS2CYSLTR2CYSLTR1P4HB
SCHEMBL5313693 0.98 EPHX2 (0.64) EPHX2PTGS2CYSLTR2CYSLTR1P4HB
SCHEMBL19066580 0.98 EPHX2 (0.64) EPHX2PTGS2CYSLTR2CYSLTR1P4HB
SCHEMBL9323113 0.94 EPHX2 (0.56) EPHX2PTGS2CYSLTR2CYSLTR1P4HB
SCHEMBL31359159 0.88 EPHX2 (0.52) EPHX2PTGS2CYSLTR2CYSLTR1P4HB
SCHEMBL10504004 0.86 PTGS2 (0.51) EPHX2PTGS2P4HBSOAT1HPGD
SCHEMBL9810708 0.84 EPHX2 (0.48) EPHX2PTGS2CYSLTR2CYSLTR1P4HB
SCHEMBL28397899 0.82 EPHX2 (0.50) EPHX2PTGS2CYSLTR2CYSLTR1P4HB
SCHEMBL28404539 0.82 EPHX2 (0.50) EPHX2PTGS2CYSLTR2CYSLTR1P4HB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1946708-B Synthesising method and benzoxathiepine intermediates PF MEDICAMENT CO LTD 2011-11-16 CN claimed
US-7902381-B2 Synthesising method and benzoxathiepine intermediates PIERRE FABRE MEDICAMENT (FR) 2011-03-08 US claimed
US-20080234499-A1 Synthesising Method and Benzoxathiepine Intermediates PIERRE FABRE MEDICAMENT (FR) 2008-09-25 US claimed
EP-1735297-B1 SYNTHESISING METHOD AND BENZOXATHIEPINE INTERMEDIATES PF MEDICAMENT (FR) 2007-10-03 EP claimed
CN-1946708-A Synthesising method and benzoxathiepine intermediates PF MEDICAMENT (FR) 2007-04-11 CN claimed
CN-114644581-B Amino acid containing aryl thiophenol or aryl selenol modified, recombinant protein, and biosynthesis method and application thereof 北京惠大生物科技有限公司 2024-07-16 CN disclosed
CN-113574041-B Bisphenol production method and polycarbonate resin production method 三菱化学株式会社 2023-10-13 CN disclosed
WO-2020189201-A1 METHOD FOR PRODUCING BISPHENOL AND METHOD FOR PRODUCING POLYCARBONATE RESIN 三菱ケミカル株式会社 2020-09-24 WO disclosed
CN-1946708-B Synthesising method and benzoxathiepine intermediates PF MEDICAMENT CO LTD 2011-11-16 CN disclosed
EP-2050769-A2 Olefin polymerization catalyst and process for olefin polymerization MITSUI CHEMICALS, INC. (JP) 2009-04-22 EP disclosed
EP-0990664-B1 CATALYST FOR OLEFIN POLYMERIZATION AND METHOD OF POLYMERIZING OLEFIN MITSUI CHEMICALS INC (JP) 2009-03-11 EP disclosed
CN-1946708-A Synthesising method and benzoxathiepine intermediates PF MEDICAMENT (FR) 2007-04-11 CN disclosed
US-6399724-B1 FOR ALPHA-OLEFINS MITSUI CHEMICALS, INC. (JP) 2002-06-04 US disclosed
EP-0990664-A1 CATALYST FOR OLEFIN POLYMERIZATION AND METHOD OF POLYMERIZING OLEFIN Mitsui Chemicals, Inc. (JP) 2000-04-05 EP disclosed
EP-0452302-A1 PREPARATION ON ORTHO-(ALKYL- OR ARYLTHIO)PHENOLS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-10-23 EP disclosed
WO-1990005718-A1 PREPARATION ON ORTHO-(ALKYL- OR ARYLTHIO)PHENOLS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-05-31 WO disclosed
EP-0369074-A1 Preparation of ortho-(alkyl-or arylthio) phenols E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-05-23 EP disclosed
US-4792633-A REACTING PHENOLS AND DISULFIDES USING ALUMINUM SILICATE CATALYSTS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1988-12-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080234499-A1 Synthesising Method and Benzoxathiepine Intermediates CYP2F1, CYP2E1, CBR1 EPHX2 447/4885PTGS2 1659/4885CYSLTR2 1954/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.