Phosphine

Phosphine

SCHEMBL20701190

P.P.P.P.P.P.P.P.P.P.P.P.P.P.P.P.c1ccc([PH](c2ccccc2)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.38
TSHR P16473 5/20 0.33
TDP1 Q9NUW8 5/20 0.33
ALOX12 P18054 3/20 0.33
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33
CA9 Q16790 2/20 0.33
CA12 O43570 1/20 0.33
GLA P06280 1/20 0.33
CA3 P07451 1/20 0.33
CA4 P22748 1/20 0.33
CA14 Q9ULX7 1/20 0.33
LMNA P02545 1/20 0.33
ACHE P22303 1/20 0.33
CA7 P43166 1/20 0.33
HSD17B10 Q99714 3/20 0.32
MAPT P10636 1/20 0.32
HPGD P15428 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
MGLL Q99685 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphine SCHEMBL28189305 1.00 ALDH1A1 (0.38) ALDH1A1TSHRTDP1ALOX12CA1
Phosphine SCHEMBL29001095 0.96 ALDH1A1 (0.35) ALDH1A1TSHRTDP1ALOX12CA1
Hydrochloric Acid SCHEMBL27550629 0.96 ALDH1A1 (0.35) ALDH1A1TSHRTDP1ALOX12CA1
Bromide SCHEMBL31057639 0.96 ALDH1A1 (0.35) ALDH1A1TSHRTDP1ALOX12CA1
Benzene SCHEMBL28207368 0.96 ALDH1A1 (0.40) ALDH1A1TSHRTDP1ALOX12CA1
SCHEMBL28748541 0.96 ALDH1A1 (0.40) ALDH1A1TSHRTDP1ALOX12CA1
SCHEMBL26674 0.96 ALDH1A1 (0.40) ALDH1A1TSHRTDP1ALOX12CA1
Hydrochloric Acid SCHEMBL8028044 0.92 ALDH1A1 (0.38) ALDH1A1TSHRTDP1ALOX12CA1
Iodide SCHEMBL8800806 0.92 ALDH1A1 (0.38) ALDH1A1TSHRTDP1ALOX12CA1
SCHEMBL9068833 0.92 ALDH1A1 (0.38) ALDH1A1TSHRTDP1ALOX12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10343912-B2 Method of synthesizing soluble polyphosphides by activation of red phosphorous in organic solvents The Florida State University Research Foundation, Inc. (US) 2019-07-09 US disclosed
US-20190039899-A1 METHOD OF CONVERSION OF RED PHOSPHOROUS TO SOLUBLE POLYPHOSPHIDES The Florida State University Research Foundation, Inc. 2019-02-07 US disclosed