Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.55 |
| ▸ | CA2 | P00918 | 2/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.55 |
| ▸ | KIF11 | P52732 | 1/20 | 0.55 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.55 |
| ▸ | DHODH | Q02127 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | CES2 | O00748 | 1/20 | 0.54 |
| ▸ | CES1 | P23141 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | MKNK1 | Q9BUB5 | 6/20 | 0.52 |
| ▸ | MKNK2 | Q9HBH9 | 6/20 | 0.52 |
| ▸ | BRD4 | O60885 | 1/20 | 0.51 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.51 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5981249 | 1.00 | CA1 (0.55) | CA1CA2CA12CA9CA14 | |
| Terephthalamide SCHEMBL17907469 | 0.93 | ALDH1A1 (0.62) | CA1CA2PARP10ALDH1A1LMNA | |
| SCHEMBL76475 | 0.93 | ALDH1A1 (0.62) | CA1CA2PARP10ALDH1A1LMNA | |
| SCHEMBL30775329 | 0.90 | ALDH1A1 (0.59) | CA1CA2PARP10ALDH1A1LMNA | |
| SCHEMBL10416433 | 0.90 | ALDH1A1 (0.59) | CA1CA2PARP10ALDH1A1LMNA | |
| Hydrazine SCHEMBL28484381 | 0.90 | ALDH1A1 (0.59) | CA1CA2PARP10ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL4376615 | 0.90 | ALDH1A1 (0.59) | CA1CA2PARP10ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL1776305 | 0.90 | ALDH1A1 (0.59) | CA1CA2PARP10ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL4879563 | 0.88 | ALDH1A1 (0.56) | CA1CA2PARP10ALDH1A1LMNA | |
| Benzene SCHEMBL28164652 | 0.88 | PARP1 (0.64) | CA1CA2PARP10DHODHALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10196373-B2 | Substituted 2-hydroxy-4-(2-(phenylsulfonamido)acetamido)benzoic acid analogs as inhibitors of STAT protein | THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) | 2019-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10196373-B2 | Substituted 2-hydroxy-4-(2-(phenylsulfonamido)acetamido)benzoic acid analogs as inhibitors of STAT protein | STAT3, STAT1, STAT4 | CA1 2562/4885CA2 389/4885CA12 4080/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.