SCHEMBL2070577

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2069857	0.83	PPARA (0.52)	CHRNB2CHRNA4PPARAFFAR1PPARD
	SCHEMBL2069858	0.83	PPARA (0.52)	CHRNB2CHRNA4PPARAFFAR1PPARD
	SCHEMBL2070135	0.80	FFAR1 (0.41)	PPARAFFAR1PPARDRAB9AALOX5
	SCHEMBL2069661	0.78	CHRNB2 (0.53)	CHRNB2CHRNA4KCNH2NPY1RCHRM2
	SCHEMBL2069652	0.75	MAPT (0.57)	PPARARAB9ANPY1RCHEK1KDM4E
	SCHEMBL2069572	0.73	CHEK1 (0.49)	PPARAFFAR1RAB9ACHEK1KDM4E
	SCHEMBL2069079	0.73	PPARA (0.48)	PPARAFFAR1PPARDAGER
	SCHEMBL3889664	0.73	TP53 (0.46)	PPARAFFAR1RAB9ACHEK1KDM4E
	SCHEMBL2071887	0.73	PPARA (0.57)	PPARAPPARDRAB9AKDM4ENPC1
	SCHEMBL2069793	0.73	PPARA (0.49)	PPARAKCNH2FFAR1PPARDALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.