SCHEMBL20707459

SCHEMBL20707459

CN(c1ccc(-c2ccc(N(c3ccc(-c4ccc(-n5c6ccccc6c6ccccc65)cc4)cc3)c3ccc4ccccc4c3)cc2)cc1)c1ccccc1-c1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.35
ATM Q13315 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
PER2 O15055 1/20 0.32
CRY1 Q16526 1/20 0.32
CRY2 Q49AN0 1/20 0.32
HDAC4 P56524 1/20 0.32
LMNA P02545 1/20 0.31
MAPT P10636 1/20 0.31
HPGD P15428 1/20 0.31
ALOX15 P16050 1/20 0.31
TSHR P16473 1/20 0.31
TUBB4A P04350 1/20 0.31
TUBB P07437 1/20 0.31
TUBA3C P0DPH7 1/20 0.31
TUBA1B P68363 1/20 0.31
TUBA4A P68366 1/20 0.31
TUBB4B P68371 1/20 0.31
TUBB3 Q13509 1/20 0.31
TUBB2A Q13885 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24948573 0.90 KDM4E (0.39) KDM4EATML3MBTL1PER2CRY1
SCHEMBL20009736 0.89 L3MBTL1 (0.41) KDM4EATML3MBTL1PER2CRY1
SCHEMBL9885487 0.89 L3MBTL1 (0.44) KDM4EATML3MBTL1HDAC4LMNA
SCHEMBL24948592 0.88 L3MBTL1 (0.41) KDM4EATML3MBTL1PER2CRY1
SCHEMBL14465439 0.88 L3MBTL1 (0.45) KDM4EATML3MBTL1HDAC4LMNA
SCHEMBL13620189 0.87 L3MBTL1 (0.46) KDM4EATML3MBTL1PER2CRY1
SCHEMBL12704840 0.87 L3MBTL1 (0.46) KDM4EATML3MBTL1PER2CRY1
SCHEMBL15894220 0.87 L3MBTL1 (0.46) KDM4EATML3MBTL1PER2CRY1
SCHEMBL24946671 0.86 KDM4E (0.35) KDM4EATML3MBTL1PER2CRY1
SCHEMBL24948359 0.86 KDM4E (0.39) KDM4EATML3MBTL1HDAC4TUBB4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3439062-A1 ORGANIC LIGHT EMITTING ELEMENT LG Chem, Ltd. (KR) 2019-02-06 EP disclosed