Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 1/20 | 0.44 |
| ▸ | FEN1 | P39748 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.42 |
| ▸ | CDK1 | P06493 | 2/20 | 0.42 |
| ▸ | CDK2 | P24941 | 2/20 | 0.42 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.42 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ATR | Q13535 | 1/20 | 0.40 |
| ▸ | PDE5A | O76074 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | AXL | P30530 | 2/20 | 0.38 |
| ▸ | CDK8 | P49336 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15426464 | 0.85 | ALOX5AP (0.43) | ALOX5APFEN1BCHENPC1KDM4E | |
| SCHEMBL10281005 | 0.81 | ALOX5AP (0.43) | ALOX5APFEN1BCHENPC1KDM4E | |
| SCHEMBL15427236 | 0.80 | ALOX5AP (0.42) | ALOX5APFEN1BCHENPC1KDM4E | |
| SCHEMBL15426441 | 0.79 | ALOX5AP (0.41) | ALOX5APFEN1BCHENPC1KDM4E | |
| SCHEMBL13608162 | 0.77 | AXL (0.51) | PDPK1CDK1CDK2MKNK2MKNK1 | |
| SCHEMBL13608548 | 0.77 | NPC1 (0.50) | PDPK1CDK1CDK2MKNK2MKNK1 | |
| SCHEMBL13608537 | 0.77 | PDGFRB (0.53) | PDPK1CDK1CDK2MKNK2MKNK1 | |
| SCHEMBL13608536 | 0.74 | PDE5A (0.44) | PDPK1CDK1CDK2MKNK2MKNK1 | |
| SCHEMBL20708854 | 0.74 | ALOX5AP (0.36) | ALOX5APFEN1BCHENPC1KDM4E | |
| SCHEMBL13608309 | 0.74 | NPC1 (0.42) | PDPK1CDK1CDK2MKNK2MKNK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3006429-B1 | FUSED HETEROCYCLIC COMPOUND AND USE FOR PEST CONTROL THEREOF | SUMITOMO CHEMICAL CO (JP) | 2019-02-06 | — | — | EP | disclosed |