SCHEMBL10281005

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15427236	0.91	ALOX5AP (0.42)	ALOX5APFEN1KDM4ENPC1ALDH1A1
	SCHEMBL15426441	0.90	ALOX5AP (0.41)	ALOX5APFEN1KDM4ENPC1ALDH1A1
	SCHEMBL15412441	0.89	ALOX5AP (0.35)	ALOX5APFEN1KDM4ENPC1ALDH1A1
	SCHEMBL20708672	0.87	DDR1 (0.37)	ALOX5APFEN1KDM4ENPC1ALDH1A1
	SCHEMBL16666271	0.85	KDM4E (0.39)	ALOX5APFEN1KDM4ENPC1ALDH1A1
	SCHEMBL15426464	0.83	ALOX5AP (0.43)	ALOX5APFEN1KDM4ENPC1ALDH1A1
	SCHEMBL20708498	0.81	ALOX5AP (0.44)	ALOX5APFEN1KDM4ENPC1ALDH1A1
	SCHEMBL15426462	0.80	NPBWR1 (0.38)	ALOX5APFEN1KDM4ENPC1ALDH1A1
	SCHEMBL20708676	0.79	NPC1 (0.49)	NPC1ALDH1A1METNPBWR1CBFB
	SCHEMBL15412801	0.79	DDR1 (0.41)	ALOX5APFEN1DDR1KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.