Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDR1 | Q08345 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 2/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
| ▸ | CASR | P41180 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | GSR | P00390 | 1/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | TACR1 | P25103 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9958588 | 0.87 | HSD11B1 (0.34) | DDR1METALOX5APFEN1CASR | |
| SCHEMBL9953119 | 0.87 | SLC6A2 (0.38) | DDR1METALOX5APFEN1CASR | |
| SCHEMBL9958612 | 0.87 | HSD11B1 (0.38) | DDR1METCASRHSD11B1PDE2A | |
| SCHEMBL9959582 | 0.81 | AGPAT2 (0.44) | DDR1HSD11B1ALDH1A1PDE2APDE10A | |
| SCHEMBL15411967 | 0.79 | POLB (0.49) | DDR1METALOX5APFEN1NPC1 | |
| SCHEMBL9959573 | 0.75 | KDM4E (0.38) | DDR1ALOX5APFEN1NPC1ATM | |
| SCHEMBL15412048 | 0.74 | POLB (0.42) | DDR1METALOX5APFEN1POLB | |
| SCHEMBL15426445 | 0.74 | KDM4E (0.38) | DDR1ALOX5APFEN1NPC1ATM | |
| SCHEMBL15426346 | 0.74 | HSD11B1 (0.39) | ALOX5APFEN1NPC1ATMHSD11B1 | |
| SCHEMBL15426458 | 0.74 | NPC1 (0.36) | ALOX5APFEN1NPC1ATMHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3006429-B1 | FUSED HETEROCYCLIC COMPOUND AND USE FOR PEST CONTROL THEREOF | SUMITOMO CHEMICAL CO (JP) | 2019-02-06 | — | — | EP | disclosed |