Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18151909 | 0.81 | CA1 (0.44) | MEN1KMT2AALDH1A1 | |
| SCHEMBL17966287 | 0.73 | CYP4F2 (0.58) | CYP4F2CYP4A11MEN1KMT2AALDH1A1 | |
| SCHEMBL31409464 | 0.72 | ALDH1A1 (0.51) | CYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL1039522 | 0.72 | HTT (0.51) | CYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL13849473 | 0.72 | CYP4F2 (0.53) | CYP4F2CYP4A11KMT2AALDH1A1CNR2 | |
| SCHEMBL8478789 | 0.69 | EGFR (0.42) | — | |
| SCHEMBL4113212 | 0.69 | CYP4F2 (0.76) | CYP4F2CYP4A11KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL13577113 | 0.68 | HTR2A (0.37) | MEN1KMT2A | |
| SCHEMBL30002088 | 0.68 | HTR2A (0.37) | MEN1KMT2A | |
| SCHEMBL2060365 | 0.68 | CYP4F2 (0.59) | CYP4F2CYP4A11ALDH1A1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3067351-B1 | COMPOUND HAVING HIGHER INHIBITION OF PROTEIN KINASE G ACTIVITY AND PREPARATION METHOD THEREFOR | JENKEM TECH CO LTD TIANJIN (CN) | 2019-02-06 | — | — | EP | disclosed |