Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | RARB | P10826 | 3/20 | 0.40 |
| ▸ | RARG | P13631 | 3/20 | 0.40 |
| ▸ | RARA | P10276 | 2/20 | 0.40 |
| ▸ | BCL9 | O00512 | 1/20 | 0.40 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.40 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.38 |
| ▸ | BAD | Q92934 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | ALB | P02768 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | RXRB | P28702 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16690678 | 0.92 | RARB (0.40) | GAARARBRARGRARABCL9 | |
| SCHEMBL18044448 | 0.92 | RARB (0.40) | GAARARBRARGRARABCL9 | |
| SCHEMBL20709025 | 0.85 | MAPT (0.44) | GAABCL9CTNNB1LMNARAB9A | |
| SCHEMBL18499050 | 0.83 | RARB (0.40) | RARBRARGRARALMNAMAPK1 | |
| SCHEMBL18151941 | 0.83 | RARB (0.40) | RARBRARGRARALMNAMAPK1 | |
| SCHEMBL18044460 | 0.83 | RARB (0.40) | RARBRARGRARALMNAMAPK1 | |
| SCHEMBL18151908 | 0.83 | RARB (0.46) | RARBRARALMNAMAPK1HTT | |
| SCHEMBL8132840 | 0.82 | EGFR (0.46) | SRD5A2LMNAMAPK1HTTRAB9A | |
| SCHEMBL18044474 | 0.78 | MAPT (0.43) | BCL9CTNNB1LMNAMAPK1HTT | |
| SCHEMBL18044486 | 0.78 | MAPT (0.43) | BCL9CTNNB1LMNAMAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3067351-B1 | COMPOUND HAVING HIGHER INHIBITION OF PROTEIN KINASE G ACTIVITY AND PREPARATION METHOD THEREFOR | JENKEM TECH CO LTD TIANJIN (CN) | 2019-02-06 | — | — | EP | disclosed |