Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20709680 | 0.92 | NPC1 (0.40) | THRAHDAC1NPC1LMNANFKB1 | |
| SCHEMBL23322555 | 0.84 | THRA (0.39) | THRAHDAC1LTB4RNPC1LMNA | |
| SCHEMBL816966 | 0.83 | NPC1 (0.40) | THRANPC1LMNANFKB1NFKB2 | |
| SCHEMBL15398137 | 0.83 | THRA (0.41) | THRANPC1LMNANFKB1NFKB2 | |
| SCHEMBL815903 | 0.82 | NPC1 (0.41) | THRANPC1LMNANFKB1NFKB2 | |
| SCHEMBL816039 | 0.82 | NPC1 (0.41) | THRANPC1LMNANFKB1NFKB2 | |
| SCHEMBL12733655 | 0.81 | THRA (0.39) | THRAMAPTKMT2A | |
| SCHEMBL12604071 | 0.81 | NPC1 (0.40) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL12604133 | 0.80 | THRA (0.38) | THRANPC1LMNANFKB1NFKB2 | |
| SCHEMBL15398086 | 0.80 | NPC1 (0.39) | NPC1LMNANFKB1NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3438134-A1 | POLYMERIZABLE COMPOSITION, CURED OBJECT, OPTICAL FILM FOR DISPLAY, AND PROCESS FOR PRODUCING CURED OBJECT | Adeka Corporation (JP) | 2019-02-06 | — | — | EP | disclosed |