⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27513090 | 0.86 | LMNA (0.46) | — | |
| SCHEMBL1978538 | 0.80 | MAPT (0.41) | — | |
| SCHEMBL526383 | 0.80 | MAPT (0.58) | — | |
| SCHEMBL17134071 | 0.79 | — | — | |
| SCHEMBL8725842 | 0.78 | MAPT (0.47) | — | |
| Hydrochloric Acid SCHEMBL9181167 | 0.77 | MAPT (0.56) | — | |
| Ammonia Solution, Strong SCHEMBL28483632 | 0.77 | MAPT (0.56) | — | |
| Ammonia Solution, Strong SCHEMBL28486254 | 0.77 | MAPT (0.56) | — | |
| SCHEMBL694336 | 0.77 | MAPT (0.43) | — | |
| Water SCHEMBL9462188 | 0.76 | LMNA (0.59) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2210 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116199667-B | Halogen substituted isoindoline compound and application thereof | 成都分迪药业有限公司 | 2024-05-03 | — | — | CN | claimed |
| WO-2023207241-A1 | HALOGEN-SUBSTITUTED ISOINDOLINE COMPOUND AND USE THEREOF | 成都分迪药业有限公司 | 2023-11-02 | — | — | WO | claimed |
| US-20230339904-A1 | ISOINDOLINONES, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS | BIOTHERYX, INC. | 2023-10-26 | — | — | US | claimed |
| CN-116199667-A | Halogen substituted isoindoline compound and application thereof | 成都分迪药业有限公司 | 2023-06-02 | — | — | CN | claimed |
| US-20220202821-A1 | SMALL MOLECULE PARG INHIBITORS AND METHODS OF USE THEREOF | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2022-06-30 | — | — | US | claimed |
| CN-114213353-A | Aryl-oxazole-oxazoline compound and preparation method and application thereof | 贵州大学 | 2022-03-22 | — | — | CN | claimed |
| EP-3201208-B1 | BORONIC ACID DERIVATIVES | MERCK PATENT GMBH (DE) | 2021-03-24 | — | — | EP | claimed |
| EP-3201207-B1 | BORONIC ACID DERIVATIVES | MERCK PATENT GMBH (DE) | 2021-02-24 | — | — | EP | claimed |
| EP-3201205-B1 | BORONIC ACID DERIVATIVES | MERCK PATENT GMBH (DE) | 2020-05-13 | — | — | EP | claimed |
| US-10640520-B2 | Boronic acid derivatives | MERCK PATENT GMBH (DE) | 2020-05-05 | — | — | US | claimed |
| WO-1993025524-A1 | FUNGICIDAL INDOLE DERIVATIVES | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) | 1993-12-23 | — | — | WO | claimed |
| US-5134150-A | Administering diaryl-substituted imidazothiazoles; antiarthritic agents | SMITHKLINE BEECHAM CORPORATION (US) | 1992-07-28 | — | — | US | claimed |
| EP-0261602-A2 | Pyridine compounds and their use | BASF Aktiengesellschaft (DE) | 1988-03-30 | — | — | EP | claimed |
| EP-0214479-A2 | Benzimidazol-2-ylpyridinium compounds | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1987-03-18 | — | — | EP | claimed |
| EP-0034349-B1 | NOVEL PYRIDINECARBOXAMIDE DERIVATIVES, A PROCESS FOR THE PREPARATION THEREOF, THE USE OF SAID DERIVATIVES AND A PHARMACEUTICAL COMPOSITION CONTAINING SAME | Tanabe Seiyaku Co., Ltd. (JP) | 1983-12-14 | — | — | EP | claimed |
| EP-0032856-B1 | 2,3-DIHYDROIMIDAZO (1,2-B) PYRIDAZINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR THERAPEUTICAL USE | SYNTHELABO (FR) | 1983-02-09 | — | — | EP | claimed |
| US-4353903-A | 2,3-Dihydro-imidazo[1,2-b]pyridazine derivatives, their preparation and use in treatment of depression | SYNTHELABO (FR) | 1982-10-12 | — | — | US | claimed |
| US-4332809-A | ANTIALLERGENS | TANABE SEIYAKU CO., LTD. (JP) | 1982-06-01 | — | — | US | claimed |
| EP-0034349-A2 | Novel pyridinecarboxamide derivatives, a process for the preparation thereof, the use of said derivatives and a pharmaceutical composition containing same | Tanabe Seiyaku Co., Ltd. (JP) | 1981-08-26 | — | — | EP | claimed |
| EP-0032856-A1 | 2,3-Dihydroimidazo (1,2-b) pyridazine derivatives, process for their preparation and their therapeutical use | SYNTHELABO (FR) | 1981-07-29 | — | — | EP | claimed |