Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 6/20 | 0.62 |
| ▸ | DRD2 | P14416 | 1/20 | 0.62 |
| ▸ | MAOB | P27338 | 1/20 | 0.62 |
| ▸ | HTR2A | P28223 | 1/20 | 0.62 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.62 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.62 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.59 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.59 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.59 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.59 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.59 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.59 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.59 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.59 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19725557 | 0.85 | KDM1A (0.67) | KDM1ADRD2MAOBHTR2ASLC6A4 | |
| SCHEMBL14032717 | 0.84 | KDM1A (0.56) | KDM1ADRD2MAOBHTR2ASLC6A4 | |
| SCHEMBL24437711 | 0.83 | KDM1A (0.72) | KDM1ADRD2MAOBHTR2ASLC6A4 | |
| SCHEMBL19092429 | 0.83 | KDM1A (0.72) | KDM1ADRD2MAOBHTR2ASLC6A4 | |
| SCHEMBL12965517 | 0.82 | GAA (0.60) | KDM1ADRD2MAOBHTR2ASLC6A4 | |
| SCHEMBL12813692 | 0.82 | KDM1A (0.57) | KDM1ADRD2MAOBHTR2ASLC6A4 | |
| SCHEMBL20843175 | 0.82 | KDM1A (0.58) | KDM1ADRD2HDAC3HDAC4HDAC1 | |
| SCHEMBL6215695 | 0.82 | CXCR4 (0.74) | KDM1AMAOBHDAC3HDAC4HDAC1 | |
| SCHEMBL20832910 | 0.82 | KDM1A (0.54) | KDM1ADRD2MAOBHTR2ASLC6A4 | |
| SCHEMBL4846613 | 0.81 | L3MBTL1 (0.76) | CXCR4L3MBTL1KCNH2CACNA1IMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019025588-A1 | METHODS OF TREATING BEHAVIOR ALTERATIONS | ORYZON GENOMICS, S.A. (ES) | 2019-02-07 | — | — | WO | disclosed |