Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | ADH1B | P00325 | 1/20 | 0.36 |
| ▸ | ADH1C | P00326 | 1/20 | 0.36 |
| ▸ | ADH1A | P07327 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | EBP | Q15125 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15346171 | 0.86 | — | — | |
| SCHEMBL25123891 | 0.81 | TSHR (0.39) | TSHRALDH1A1 | |
| SCHEMBL18951096 | 0.80 | TSHR (0.37) | TSHRALDH1A1LMNAEBP | |
| SCHEMBL7673247 | 0.79 | ADH1B (0.48) | TSHRALDH1A1ADH1BADH1CADH1A | |
| SCHEMBL2478778 | 0.77 | HRH4 (0.42) | TSHRALDH1A1ADH1BADH1CADH1A | |
| SCHEMBL1242598 | 0.77 | TSHR (0.45) | TSHRALDH1A1CA2LMNACYP1A2 | |
| SCHEMBL9624660 | 0.77 | HRH4 (0.47) | TSHRALDH1A1ADH1BADH1CADH1A | |
| SCHEMBL2483497 | 0.75 | HRH4 (0.48) | TSHRALDH1A1ADH1BADH1CADH1A | |
| SCHEMBL10045260 | 0.75 | CYP2C19 (0.45) | TSHRALDH1A1ADH1BADH1CADH1A | |
| SCHEMBL24379824 | 0.75 | HRH4 (0.48) | TSHRALDH1A1ADH1BADH1CADH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023055920-A1 | MODULATORS OF TRPML, THEIR COMPOSITIONS AND METHODS OF USE | CARAWAY THERAPEUTICS, INC. (US) | 2023-04-06 | — | — | WO | disclosed |
| US-20190043635-A1 | PHOTOSENSITIVE REDUCIBLE SILVER ION-CONTAINING COMPOSITIONS | KODAK AVIATION LEASING LLC | 2019-02-07 | — | — | US | disclosed |